Methods of Administration

There are several routes of administration of Natural Hormone Replacement Therapy (NHRT). Each has its own advantages. Each woman has individualized responses to the delivery method and hormone activity.

Oral: NHRT is available in capsule from most of the compounding pharmacies in this area. However, the hormone must first pass through the stomach, duodenum and liver before reaching the target organs.

Trans dermal: This method is frequently preferred because it passes directly into the blood stream via the capillaries. There is no first pass through the liver and therefore less production of analogues that may cause problems.

Trans vaginal: This method is the least favored unless there is a specific need to strengthen the vaginal mucosa and promote lubrication.

To Contact Us:

Phone: 248 626-7544

Fax: 248 626-9698


Hormone Replacement Therapy


John Lee, M.D. makes excellent arguments in his books for the use of progesterone not only during menopause, but also for several years preceding menopause to preclude Osteopenia and the development of other menopausal symptoms. These are valid, scientifically based views that are well researched and documented. He emphasizes that estrogen should NEVER be given to women who still have a uterus without progesterone. This concurrent administration helps prevent endometrial cancer. (What Your Doctor May NOT Tell You About Menopause, John Lee, M.D.)

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Bio-identical Hormones

There has been considerable controversy in recent years about the differences between “synthetic” hormones and “natural” hormones extracted from either plant or animal sources. The traditional-conventional western medical “experts” have espoused the use of synthetic hormones because the quality and consistency of the products are quite predictable. However, many studies have proven that “natural” hormones or those extracted from plant (phyto-estrogens, etc.) and animal models have the quality and efficacy comparable or exceeding the products produced by pharmaceutical manufacturers. The staff of Farmington Medical Center recommends the product that best suits the metabolic, physical and emotional needs of the individual patient. Patient information and education is of paramount importance. Mutual trust and respect are the keys to honest, forthright communication.


Estrogen is a group of hormones produced primarily by the ovaries from puberty to menopause. After menopause, some fat cells will continue to produce estrogen in modest amounts. The three most active estrogen hormones are Estrone (E1) Estradiol (E2) and Estriol (E3). Each of these has varying degrees of activity at the cellular level. Estrone is believed to be the hormone most related to the development of breast cancer. Estriol is the hormone most produced in large amounts during pregnancy and is believed to be protective against breast cancer. High levels of Estriol are found in vegetarians and Asian women both of whom have lower breast cancer rates. Estradiol is the estrogen most produced by the female ovaries and is converted biochemically into the other estrogens. It also has salutary effects for secondary gender characteristics including breast development and vulvar fat pad development.

Chemical breakdown of EstrogenDr. John Lee


While estrogen and progesterone do help prevent osteopenia, cardiovascular and brain degradation, testosterone is key to providing the optimal effect of these “female hormones”. Testosterone actually enhances development of new bone, strengthens connective tissue, muscles and mucosa, and definitely improves cognitive function of the brain. The salutary effect of improved mood and libido is without question the reason most women request this HRT.